
Medicines Discovery Award Program
(MDAP)
What is the MDAP?
MDAP is a competitive incubator and accelerator program designed to identify and advance promising early-stage drug discovery from investigators at the University at Buffalo and the University of Rochester. Award amounts range between $250K to $7.5M in total program support over five years, reviewed annually. Successful projects exit as either a negotiated licensing transaction to a strategic partner or as a new startup company launched by Empire Discovery Institute.
Program Structure
Following entry, the program is assigned a scientific project team (Project Team) comprised of the principal investigators (PIs), select Advisory Board members, and a project manager. This Project Team develops a tailored work plan, outlining milestone objectives, budget, and a performance timeline. A portion or the entire work plan may be executed by the PIs under a sponsored research arrangement between Empire Discovery Institute and the partner research institution. Further, Empire Discovery Institute coordinates and manages the funded research project through its network of contract research organizations, specialty service providers, pharmaceutical industry experts, and consultants. Work performed in the PI’s laboratory receives financial payments linked to specific work plan-driven milestones. Advancement to the next level of support is determined on an annual basis by Empire Discovery Institute's Advisory Board.
ACCEPTED PROJECTS RECIEVE:
From expert guidance and funding opportunities to promotional support and access to specialized tools, each selected project will be equipped with the essential support needed to thrive throughout the program and beyond.
CLINICAL DEVELOPMENT STRATEGY, INTELLECTUAL PROPERTY FILING, REGULATORY STRATEGY, AND IND PREPARATION
CLINICAL DEVELOPMENT STRATEGY, INTELLECTUAL PROPERTY FILING, REGULATORY STRATEGY, AND IND PREPARATION
BUSINESS DEVELOPMENT AND PRODUCT COMMERCIALIZATION
COMPANY INCORPORATION AND MANAGEMENT
PROJECT MANAGEMENT AND PLANNING
DRUG DISCOVERY & DEVELOPMENT EXPERTISE



Drug discovery and development expertise

Company incorporation and management
Clinical development strategy, intellectual property filing, regulatory strategy, and IND preparation

Eligible Project Resources
Programs of interest
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Novel insights into disease pathways or molecular mechanisms of human disease that have a clear mechanism of action or possess a well-defined genetic basis.
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Research in the fields of cancer, neurological CNS conditions, autoimmune, rare and orphan diseases, and platform technologies with broad therapeutic potential.
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Projects with a strong biomarker component to support translational development.
Application Process
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Applications accepted on a rolling basis, unless otherwise requested by Empire Discovery Institute under a formal Request for Proposal (RFP).
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After an initial proposal review, selected investigators are invited to give a 30-minute presentation to the Empire Discovery Institute, followed by a 30-minute Q&A.
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The presentation and the proposal are evaluated against Empire Discovery Institute's "market-back, science-forward" framework.
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Proposals receiving high scores are recommended to the Empire Discovery Institute’s board for approval and entry into MDAP.
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Unsuccessful applications receive constructive feedback and are encouraged to reapply in the future.
Eligibility Requirements
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Investigators must have a faculty position at the University at Buffalo or the University of Rochester.
For more information,
Molly Mesko, MBA
Director of Portfolio Development and Alliance Management
E-mail: meskom@discoverEDl.org
Our Values
1. Innovation
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2. Collaboration
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3. impact
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What We Do
Target to hit
HIT TO LEAD
Lead Optimization
Pre-Clinical
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