Our Approach
Empire Discovery Institute evaluates academic proposals through a unique “market-back science-forward” framework to ensure each selected project combines strong scientific merit with commercial potential.
Market Back
Market-Back assesses how each proposal aligns with current and emerging pharmaceutical priorities and its potential to address significant unmet medical needs.
Key Evaluation Criteria:
1.
Unmet Need: The program addresses a critical medical gap within a given disease or therapeutic area.
2.
Strategic Fit: Alignment with the pharmaceutical industry's top therapeutic areas of interest, both scientifically and commercially.
3.
Competitiveness: Differentiation with respect to the nature and stages of comparable programs in development.
4.
Market Opportunity: Size of the potential market and projected revenue streams across key global regions.
Science-Forward evaluates the technical strength and likelihood of success from target to-hit, hit-to-lead, lead optimization, to IND-enabling studies, focusing on de-risking and value creation.
Key Evaluation Criteria:
1.
Feasibility: In-depth analysis of a program's scientific and technical feasibility, combined with a prediction of technical and commercial success.
2.
Intellectual Property: Strength of current IP and the ability to develop a defensible position, including composition of matter and/or methods of use claims.
3.
Proof-of-Concept Potential: Likelihood of achieving early "proof-of-concept" through measurable surrogate endpoints and efficacy, and early demonstration of appropriate "drug-like" properties.
4.
Path to Approval: Clear and achievable clinical and regulatory pathway to product approval.
5.
PI’s Commitment: Enthusiasm and commitment level of the project PI to regularly engage with the Advisory Board, external partners, and investors.
Science forward
Eligible Resources
Program accepted into Empire Discovery Institute's accelerator gain access to a powerful set of resources:
Commercial
Strategy
A clearly defined commercial path and exit strategy tailed to the
asset.
Milestone-Driven Work Plans
Jointly developed work plans with clear,
value-creating milestones that advance programs toward patient and commercial impact.
Project teams
Customized project teams dedicated to ensuring scientific and
operational excellence.
Funding
Access to funding, technical capabilities, and guidance from seasoned
pharmaceutical industry experts.
Our Values
1. Innovation
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2. Collaboration
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3. impact
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What We Do
Target to hit
HIT TO LEAD
Lead Optimization
Pre-Clinical
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